Image 1: Chronic wound infection#1, CLSM, 63x, S. aureus
Image 2: Chronic wound infection#2, CLSM, 63x, S. aureus
Image 3: Chronic wound infection#3, CLSM, 63x, S. aureus
Image 3: Chronic wound infection#4, CLSM, 63x, P. aeruginosa
Figure 1: Schematic drawing of a chronic wound with different species of bacteria heterogeneously distributed in various sizes of biofilms and as single cells from the top to the deeper layers of the wound.
Four confocal microscopy images from patients with a chronic leg wound. Images show biofilms in different sizes with scattered single cells. Bacteria were stained with a universal 16S PNA-FISH probe (red), and eukaryotic cells were counter-stained with DAPI (blue).
Figure 2: List of current assumptions regarding biofilms in wounds.
Acknowledgement: The figures were created using BioRender.com.
Key literature
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