New Technologies - Tissue Damage Repair
This document aims to provide a comprehensive review of tissue damage repair therapies — offering healthcare professionals, researchers, and stakeholders the latest evidence-based guidance to improve wound care strategies. Additionally, it will highlight challenges to clinical adoption and explore regulatory considerations for these specific therapies.
This initiative aims to strengthen and broaden the understanding of the therapies in wound healing
treatments. It seeks to identify and discuss the potential of these technologies in promoting tissue
regeneration, as well as the barriers to their adoption in routine clinical practice. The key objectives
are:
- Provide a comprehensive overview of dermal matrices and oxygen delivery therapies,
focusing on their roles in wound healing. - Evaluate the current and emerging evidence surrounding these therapies, including their
clinical applications, effectiveness, and mechanisms of action in tissue regeneration. - Identify technical and practical challenges involved in the integration of these therapies
into clinical practice, highlighting the experiences and insights of key opinion leaders in
wound care. - Explore regulatory and safety considerations related to the use of these therapies in
wound management, including guidelines for monitoring and controlling their application
in clinical settings. - Foster further innovation and collaboration by providing a clear foundation of evidence
that encourages the development of new applications, standards, and practices to
improve patient outcomes.

Author group
- Alberto Piaggesi (Editor), Italy
- Alexandra P. Marques, Portugal
- Carlotta Scarpa, Italy
- Edwin Den Braber, Netherlands
- Franco Bassetto, Italy
- Gerit Mulder, US
- Giuseppe Turchetti, Italy
- Ibby Younis, UK
Project timeline
- Project initiation: February 2025
- Expected publication: May 2026
Project supporters
This project is supported by: