Antimicrobials and non-healing wounds: An update

The publication highlights the changes in knowledge regarding use of antimicrobials since 2013 and develops updated principles of antimicrobial stewardship, including an algorithm on how to prescribe antimicrobials in non-healing wounds.


This EWMA Document provides an update on the controversies and hopes published in the 2013 document: Antimicrobials and Non-healing Wounds. Evidence, Controversies and suggestions.

The aims are to:

  • Highlight current knowledge regarding the use of antimicrobial agents, particularly in nonhealing
  • wounds
  • Discuss new information and progress in this field since 2013
  • Offer recommendations for future actions
  • Provide practical guidance for clinical practice concerning the appropriate use of antibiotics and antiseptics in wound management


Addressing the urgent need for antimicrobial stewardship in wound care

Given the societal value of antimicrobials and their diminishing effectiveness due to antimicrobial resistance, the WHO is now recommending member states to strengthen national stewardship. Still, there are currently no international or coordinated legislative or regulatory mandates designed to optimize the use of antimicrobials through stewardship. However, antimicrobial stewardship programmes are increasingly advocated as means to decrease misuse of antimicrobial agents.

Along with infection prevention and control, hand hygiene, and surveillance, antimicrobial stewardship is considered a key strategy in local and national programmes aiming to prevent the emergence of antimicrobial resistance and decrease preventable healthcare associated infections.

EWMA is now taking action and introducing together with BSAC a tailored stewardship concept to wound care practitioners.


Authors & Editors

  • Sebastian Probst, Switzerland
  • Jan Apelqvist, Sweden
  • Thomas Bjarnsholt, Denmark
  • Benjamin Lipsky, USA
  • Karen Ousey, UK
  • Edgar Peters, the Netherlands

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