EWMA Conference 2018

HOW DO MAGGOTS OPERATE?

Session Objectives

Larval therapy is widely used today for the treatment of acute and chronic wounds in patients. Annually, more than 15.000 patients receive larval therapy in Europe. Although larvae were already applied on wounds in ancient times, the exact mechanisms of action of larvae in wound treatment are only recently becoming better understood. The US Food and Drug Administration registered maggot debridement therapy (510(k) #33391 as a wound treatment method in 2004. The Inspectie voor de Gezondheidszorg (IGZ) in the Netherlands approved the larva Lucilia sericata as an unregistered medicine in 2014. Three randomized clinical trials (RCTs) have shown the debridement potential of larvae, while other beneficial effects of larvae on wounds, including anti-infection, immunomodulation, angiogenesis, and tissue remodeling and regeneration, have been widely reported clinically and are supported by numerous in vitro studies.

More research and development of evidence-based wound therapies are of the utmost importance, because treatment of (chronic) wounds is a daily and major problem in clinical practice. This problem is even increasing in the near future by the incidence of diabetes and ageing in the population. Larval therapy is an essential addition to your (limited) evidence-based wound care arsenal.
This workshop gives an overview of the clinical indications of the therapy, the scientific background and future research. Furthermore, you can practice larval therapy on models.

Session content:

Chair: Gwendolyn Cazander

Gwendolyn Cazander, Vascular Surgeon, Wound Expertise Center, Ikazia, Rotterdam, NL
Introduction about larval therapy. 5 min

Gwendolyn Cazander, Vascular Surgeon, Wound Expertise Center, Ikazia, Rotterdam, NL   
Clinical application of larvae on wounds. 15 min

Peter. H. Nibbering, Medical microbiologist/immunologist, Medical microbiologist/immunologist, LUMC, Leiden, NL   
The science behind the larva. About the past and the future. 15 min

Louk van Doorn, Dept. of Vascular Surgery, Leiden University Medical Center, NL
Practical application of larvae on wound models. 15 min